While the general guidelines recommend starting at age 55, you may need PSA screening between the ages of 40 and 54 if you: Have at least one first-degree relative (such as your father or brother) who has had prostate cancer. Have at least two extended family members who have had prostate cancer.
When should you have a PSA test?
Men ages 45 to 49 should have a baseline PSA test. If the PSA level is 3 ng / mL or higher, men should talk with their doctor about having a biopsy of the prostate. If the PSA level is between 1 and 3 ng / mL, men should see their doctor for another PSA test every two to four years.
Why is PSA not recommended?
Expert guidelines don't recommend PSA screening in men 70 and older. Because of their more limited lifespan, these men are less likely to benefit from early detection of low-risk cancer. One reason is that there may be simply less time for the condition to become life threatening in most men.