Because cough is a common problem associated with angiotensin-converting enzyme inhibitors (ACEIs), many of the ARB studies have addressed this symptom. Overall, the frequency of cough in ARB-treated patients is significantly lower than in those taking ACEIs or diuretics, and comparable to that with placebo.

Can ARBs cause dry cough?

Rates of side effects, such as headache and dizziness, are about the same for ACEIs and ARBs. The only significant difference is the rate of dry cough. Cough occurs for 1–3 percent of people taking an ARB, and cough is about three times more common for people taking an ACEI.

Why do ARBs not cause cough?

Dry cough is a well known side effect of ACE inhibitors due to inhibition of metabolism of bradykinin and kallikren system by the same enzyme which converts Angiotensin I into Angiotensin II. But ARBs have nothing to do with this enzyme so they don't disturb the metabolismof bradykinnin.