Epigenetic modifications refer to changes in the gene expression that are not caused by changes in the DNA sequences but are due to events like DNA methylations, histone modifications, miRNA expression modulation, etc.

What are types of epigenetic modifications?

Epigenetic modifications are heritable chemical or physical changes in chromatin. There are two types of epigenetic modifications – DNA methylation and histone modifications (16).

What are epigenetic modifiers?

The easiest of these to describe are the epigenetic modifiers — that is, the genes whose products modify the epigenome directly through DNA methylation, the post-translational modification of chromatin or the alteration of the structure of chromatin.