You can safely remove anything in the folder, but you may not be able to delete items that are in use. Likely safe locations to delete files and folders from: C:\Windows > Temp. C:\Users > username > AppData > Local > Temp.

How do I free up AppData space?

To clean up the AppData directory, you can use the built-in Windows 10 Disk Cleanup Wizard. Go to Settings > System > Storage and select your system drive. Select Temporary files. Select Temporary Internet Files and Temporary files and click the Remove Files button.

What is the AppData folder used for?

The AppData folder includes application settings, files, and data unique to the applications on your Windows PC. The folder is hidden by default in Windows File Explorer and has three hidden sub-folders: Local, LocalLow, and Roaming. You won't use this folder very often, but this is where your important files reside.