Bone is primarily vascularized by an arterial network, but within the bone marrow cavity and the Haversian channels the vasculature branches into thin-walled capillaries, whose fundamental role is the exchange of nutrients and signals between blood and bone cells [3].

Why is bone highly vascularized?

Bone is a richly vascularized connective tissue. As the main source of oxygen, nutrients, hormones, neurotransmitters and growth factors delivered to the bone cells, vasculature is indispensable for appropriate bone development, regeneration and remodeling.

Is bone poorly vascularized?

Although the skeletal vascular network is generally robust, some bones are poorly perfused.