The reliability of modern Ducati's should be of little concern. However, the maintenance can be costly depending on which model and how many miles you ride. The valve checks at 6000 miles aren't a huge deal unless you are riding big miles. The 2V (S2R) will be less expensive to maintain than the 4V (S4RS).

Why is Ducati so unreliable?

Why Is The Panigale V4 Bad On Reliability

Chief among them was the V4's clutch fade problem. It resulted in a choppy ride and jolts every time you execute a gear shift. Another major issue and potentially life-threatening was a faulty fuel system.

How long do Ducati engines last?

Registered. A Ducati 4-valve engine is not fully broken-in until 15-20,000 mi show on the clock. A properly maintained (and loved) motor could last as many as 348,000,000,000 mi.