Nether quartz ore can be mined with any pickaxe, or it drops nothing. If mined with Silk Touch, the block drops itself. Otherwise, it drops 1 Nether quartz (or more with Fortune).

Does Fortune III work on quartz?

From my experience, it does work on nether quartz. "In the beginning the Universe was created. This has made a lot of people very angry and been widely regarded as a bad move."

How much quartz do you get with Fortune 3?

#1 - Fortune enchanted pickaxes

When broken with a standard pickaxe, Nether Quartz blocks will only drop one unit of quartz. However, with a powerful enchantment like Fortune III on a strong pickaxe like the diamond pickaxe, each Nether Quartz block can drop as many as four units of quartz.