Seizure threshold is an important parameter to decide the dose of ECT. Medications like benzodiazepines, barbiturate and antiepileptics commonly increase the seizure threshold.

What drugs lower the seizure threshold?

Medications that lower seizure threshold include the antidepressant and nicotinic antagonist bupropion, the atypical opioid analgesics tramadol and tapentadol, reserpine, theophylline, antibiotics (Fluoroquinolones, imipenem, penicillins, cephalosporins, metronidazole, isoniazid) and volatile anesthetics.

Do Benzos prevent seizures?

What are Benzodiazepine anticonvulsants? Benzodiazepine anticonvulsants refer to those benzodiazepines that are also effective at controlling or preventing convulsions or seizures. All benzodiazepines act on gamma-aminobutyric acid-A (GABA-A) receptors, but there are several different GABA-A receptor subtypes.