Google's John Mueller confirmed on Twitter that it may be worth looking into compressing your HTML and CSS. ... Sometimes minifying HTML & CSS can reduce the size of the files, so it can certainly be worth looking into that.

Should you minimize HTML?

Minifying your HTML can improve your PageSpeed Score, decrease your page's render and load times, and reduce your overall page size.

Does Minifying JavaScript improve performance?

Minifying strips out all comments, superfluous white space and shortens variable names. It thus reduces download time for your JavaScript files as they are (usually) a lot smaller in filesize. So, yes it does improve performance. The obfuscation shouldn't adversely affect performance.