Acute Myocardial Infarction in Patients With Diabetes
DKA precipitated by acute MI increases the mortality rate in these patients to nearly 85%. During DKA events, the myocardium is denied glucose uptake because of high levels of ketones and free fatty acids, leading to myocardial ischemia.
What situations can cause DKA?
Other possible triggers of diabetic ketoacidosis include:
- Physical or emotional trauma.
- Heart attack or stroke.
- Pancreatitis.
- Pregnancy.
- Alcohol or drug abuse, particularly cocaine.
- Certain medications, such as corticosteroids and some diuretics.
What is the most common cause of diabetic ketoacidosis?
DKA is a state of absolute or relative insulin deficiency aggravated by ensuing hyperglycemia, dehydration, and acidosis-producing derangements in intermediary metabolism. The most common causes are underlying infection, disruption of insulin treatment, and new onset of diabetes.
