Chimerism genetic testing is used to monitor the success of haemopoietic stem cell transplantation (HSCT) by evaluating the ratio of donor and recipient DNA in the recipient's blood or bone marrow.

What is chimerism analysis?

Chimerism analysis is used after blood stem cell transplant to monitor the success of engraftment or to detect early graft failure, rejection and relapse. The test evaluates the mixture of donor and recipient DNA in the recipient's blood or bone marrow.

How is chimerism diagnosed?

Chimerism testing (engraftment analysis) is performed for patients who have received a hematopoietic stem cell transplant. The test involves identifying the genetic profiles of the recipient and of the donor and then evaluating the extent of mixture in the recipient's blood or bone marrow.