Stimulants, such as Ritalin and Adderall, are common in the treatment of attention-deficit hyperactivity disorder (ADHD). Both Ritalin and Adderall cause pupils to dilate. SSRIs enhance the effects of serotonin in the brain. They're the most commonly prescribed treatment for depression.

Why does Adderall make your pupils dilate?

Benzodiazepine drugs like Xanax can also cause pupils to dilate because they affect the activity of the neurotransmitter GABA, which has a muscle-relaxing effect. Stimulant medications like Ritalin and Adderall, which are used to treat ADHD, are also among drugs that cause dilated pupils.

What drugs dilate and constrict pupils?

Ketamine – This common party drug often induces rapid, involuntary eye movement and dilated pupils. Opioids (hydrocodone, morphine, Oxycontin, fentanyl etc.) – Both legal and illicit opioids constrict the pupils leading to their pinpoint reaction.