'Presume' is the word to use if you're making an informed guess based on reasonable evidence. If you're making a guess based on little or no evidence, the word to use is 'assume'.
How do you use presuming in a sentence?
Presuming sentence example
Simply presuming that a science advancement has been achieved to enable the story is fine, and used all the time. No, Martha Boyd had no idea where her mother was nor did she know the woman's destination, presuming Patsy had one.
How do you use the word presume?
Assume is a verb that means to suppose, to take for granted, to take upon, to don, or to undertake. In the shared meaning of “to suppose,” presume is usually used when you suppose based on probability, while assume is used when you suppose without any evidence.