Our results indicate a specific alteration of hippocampal interneurons in bipolar disorder, likely resulting in hippocampal dysfunction.

How does the hippocampus affect bipolar disorder?

Bipolar Disorder Can Shrink Part of Your Brain's Hippocampus

The left side of the hippocampus regulates verbal and visual memory. This part of the brain also helps regulate how you respond to situations emotionally. When your mood shifts, your hippocampus changes shapes and shrinks.

What do interneurons do?

As the name suggests, interneurons are the ones in between - they connect spinal motor and sensory neurons. As well as transferring signals between sensory and motor neurons, interneurons can also communicate with each other, forming circuits of various complexity. They are multipolar, just like motor neurons.