Dicumarol is an coumarin-like compound found in sweet clover. It is used as an oral anticoagulant and acts by inhibiting the hepatic synthesis of vitamin K-dependent coagulation factors (prothrombin and factors VII, IX, and X).

What is Dicumarol prescribed for?

Introduction. Dicumarol, like warfarin, is a 4-hydroxycoumarin-derived anticoagulant that is used for the treatment of thromboembolic conditions. It was the first of the oral anticoagulants to be isolated and used clinically.

Who discovered Dicumarol?

History. Dicoumarol was isolated by Karl Link's laboratory at University of Wisconsin, six years after a farmer had brought a dead cow and a milk can full of uncoagulated blood to an agricultural extension station of the university.