Raphael Santiago and Isabelle Lightwood's relationship took an unexpected, but celebrated, turn during the Season 2A finale of Freeform's 'Shadowhunters' when Raphael revealed to Izzy that he identifies as asexual.

Who does Izzy date in shadowhunters?

Simon Lewis (boyfriend)

What happened between Raphael and Isabelle?

Isabelle, who was already suffering from withdrawal, begged Raphael to bite her. Though he refused at first, he eventually gave in. When the effects of his blood wore off, Isabelle met with him again. When Raphael refused her request, she baited him into biting her by injuring herself.