Due to its clotting action, topical thrombin should only be applied to the surface of bleeding tissue. It should never be injected systemically, because that can lead to extensive intravascular clotting and death.

Can you inject thrombin?

Thrombin is injected through 25-gauge needle while flow pattern is moni- tored with sonographic probe. coagulation lengthens compression time and decreases success rates.

How do you apply topical thrombin?

Use In Conjunction With Absorbable Gelatin Sponge

Immerse sponge strips of the desired size in THROMBIN-JMI solution. Knead the sponge strips vigorously with moistened, gloved fingers to remove trapped air, thereby facilitating saturation of the sponge. Apply saturated sponge to bleeding area.