Yes cell scrapping lyse adherent cell (V-79 cell line) ,which is comparably higher than trypsinization and a citrate buffer treatment .

When would you use a cell scraper?

Cell Scraper is sterile, individually wrapped, non-pyrogenic, disposable, and have a polystyrene handle and a low-density polyethylene blade. They are useful for harvesting cells or cell lysates and are designed for use with Tissue Culture-Treated Dishes (Catalog #38046) and Cell Culture Flasks (Catalog #38072).

What can lyse a cell?

Several methods are commonly used to physically lyse cells, including mechanical disruption, liquid homogenization, high frequency sound waves, freeze/thaw cycles and manual grinding. These methods have been reviewed extensively in protein methods books.