List of types and examples of generic and brand name vasodilators
benazepril (Lotensin)captopril (Capoten)enalapril (Vasotec, Epaned)fosinopril (Monopril)lisinopril (Prinivil, Zestril)moexipril (Univasc)perindopril (Aceon)quinapril (Accupril)
Which drugs are direct vasodilators?
Indications
Direct-acting vasodilators (hydralazine, minoxidil, nitrates, nitroprusside)Calcium channel blockers (verapamil, diltiazem, nifedipine, amlodipine)An antagonist of the renin-angiotensin-aldosterone system (angiotensin receptor blockers, angiotensin-converting-enzyme inhibitors)
What is the most effective vasodilator?
CGRP: a novel neuropeptide from the calcitonin gene is the most potent vasodilator known. J Hypertens Suppl.
Is Amlodipine a vasodilator?
Dihydropyridines — The dihydropyridines, including nifedipine, isradipine, felodipine, nicardipine, nisoldipine, lacidipine, amlodipine, and levamlodipine are potent vasodilators that have little or no negative effect clinically upon cardiac contractility or conduction.
Is nifedipine a vasodilator?
Nifedipine reduces blood pressure predominantly by reducing systemic vascular resistance due to a direct vasodilating action on the arterioles.
Is Viagra a vasodilator?
PDE5 inhibitors, including VIAGRA, and alpha-adrenergic blocking agents are both vasodilators with blood pressure lowering effects. When vasodilators are used in combination, an additive effect on blood pressure may occur.
Is verapamil a vasodilator?
Background The calcium antagonist verapamil is a vasodilator drug that has been shown to increase oxygen extraction of ischemic tissues in coronary and peripheral vascular disease.
Is dopamine a vasodilator?
In the cardiovascular system, dopamine’s effects have been studied extensively and are well characterized. A unique property of dopamine is that low doses cause vasodilation and decrease systemic blood pressure, whereas high doses cause vasoconstriction and increase systemic blood pressure.
What do vasodilators treat?
These drugs treat a variety of conditions, including high blood pressure. Vasodilators are medications that open (dilate) blood vessels. They affect the muscles in the walls of the arteries and veins, preventing the muscles from tightening and the walls from narrowing.
Is hydralazine a direct vasodilator?
Hydralazine is a direct vasodilator used orally to treat essential hypertension, among other diseases, and intravenously to rapidly reduce blood pressure in hypertensive urgency or emergency. Per JNC 8 guidelines, it is not a first-line agent for the treatment of essential hypertension.
Is Ibuprofen a vasodilator?
Compared to aspirin, ibuprofen has a milder and shorter-lived antiplatelet effect. It has also been shown that it can have a vasodilator effect, dilating mainly coronary arteries but also others can be effected.
Is aspirin a vasodilator?
It has been shown that aspirin has unique vasodilator action in vivo, offering an explanation for the unique blood pressure effect of aspirin. In the present study, we investigate the mechanism whereby salicylates (aspirin and sodium salicylate) dilate blood vessels.
What drugs increase blood flow?
Pentoxifylline is used to improve blood flow in patients with circulation problems to reduce aching, cramping, and tiredness in the hands and feet. It works by decreasing the thickness (viscosity) of blood. This change allows your blood to flow more easily, especially in the small blood vessels of the hands and feet.
Are beta blockers vasodilators?
beta 1-blockers with beta 2 agonist activity are vasodilatory because they activate postsynaptic beta 2 receptors on vascular smooth muscle cell membranes, via the formation of cyclic AMP.
Is diltiazem a vasodilator?
Thus, the vasodilator properties of diltiazem can be utilized for effective long-term treatment of hypertension. The possibility of once-daily dosing may prove useful with respect to drug compliance in the long-term treatment of a generally asymptomatic disease such as hypertension.
Is methyldopa a direct vasodilator?
Central Sympathetic Agents and Direct Vasodilators
Between 10% and 20% of patients who are treated with α-methyldopa (≥1 g/d) over a period of several months develop one or more of these adverse events.
Is losartan a vasodilator?
Background: Losartan is a new angiotensin II type 1 (AT1) receptor antagonist and an antihypertensive drug. Nitric oxide is a vasodilating agent and endothelins are powerful vasoconstrictors, both synthesized by and released from endothelial cells.