This medication is used to treat a high level of potassium in your blood. Too much potassium in your blood can sometimes cause heart rhythm problems. Sodium polystyrene sulfonate works by helping your body get rid of extra potassium.
Is Kayexalate available OTC?
Kayexalate is a prescription medicine used to treat the symptoms of Hyperkalemia. Kayexalate may be used alone or with other medications.
What is the brand name of sodium polystyrene sulfonate?
Sodium polystyrene sulfonate is available as brand name Kayexalate and as generic brands Kalexate, Kionex, and SPS, as well as non-branded generics.
Is Kayexalate a trade name?
The Kayexalate brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Why is Kayexalate used in renal patients?
Management of hyperkalemia is dependent upon the extent of potassium increase and associated patient symptoms. Sodium polystyrene sulfonate (SPS) (Kayexalate®) is a cation exchange resin that trades sodium ions for potassium ions, mostly in the large intestine, to enhance the fecal elimination of excess potassium.
When should Kayexalate be given?
ORAL DOSING
When taken by mouth, KAYEXALATE should be taken at least 3 hours before or 3 hours after other oral medications. For patients with gastroparesis (a condition preventing your stomach from emptying properly), a 6-hour separation should be considered.
Is Kayexalate expensive?
The cost for Kayexalate oral and rectal powder – is around $804 for a supply of 453.6 grams, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What can I use instead of Kayexalate?
The FDA approved oral sodium zirconium cyclosilicate (ZS-9), to be marketed as Lokelma, for the treatment of hyperkalemia. The drug seems to work better than sodium polystyrene sulfonate (Kayexalate), reducing serum potassium levels within an hour and restoring normal levels after about 2 hours in most patients.
Can Kayexalate be given outpatient?
Moreover, it may not have any acute effect at all; some studies have demonstrated that, when taken for multiple days, kayexalate can effectively treat mild hyperkalemia in the outpatient setting, but there is almost no data supporting the use of kayexalate in moderate or severe hyperkalemia.
Why was Kayexalate discontinued?
However, the U.S. Food and Drug Administration (FDA) has issued a warning to avoid Kayexalate administration with sorbitol due to the risk of colonic necrosis associated with sorbitol administration.
Why is Kayexalate given for hyperkalemia?
Kayexalate (Sodium polystyerene sulfonate) is a cation-exchange resin that was approved in 1958 as a treatment for hyperkalemia by helping to exchange sodium for potassium in the colon and thus excreting potassium from the body. This drug has been a standard part of treatment of hyperkalemia for decades.
When is Kayexalate contraindicated?
KAYEXALATE is contraindicated in the following conditions: patients with hypokalemia, patients with a history of hypersensitivity to polystyrene sulfonate resins, obstructive bowel disease, neonates with reduced gut motility (postoperatively or drug induced) and oral administration in neonates (see PRECAUTIONS).
How do you pronounce Kayexalate?
Phonetic spelling of Kayexalate. kayex-alate.Meanings for Kayexalate.Examples of in a sentence. Kayexalate and Patiromer effective in lowering serum potassium concentration: Study.
Does Kayexalate induce diarrhea?
KAYEXALATE may cause some degree of gastric irritation. Anorexia, nausea, vomiting, and constipation may occur especially if high doses are given. Also, hypokalemia, hypocalcemia, and significant sodium retention, and their related clinical manifestations, may occur (see WARNINGS). Occasionally diarrhea develops.
Can dialysis patients take Kayexalate?
How do I take Kayexalate®? hemodialysis staff tells you to, even if you miss a dialysis treatment. Take it at least 3 hours before or 3 hours after any other oral (taken by mouth) medications. Take this medication for as long as the hemodialysis staff tells you to.
Can Kayexalate be given daily?
2.2 Recommended Dosage
Oral The average total daily adult dose of KAYEXALATE is 15 g to 60 g, administered as a 15-g dose (four level teaspoons), one to four times daily.
What type of drug is Kayexalate?
What Is Kayexalate? Kayexalate (sodium polystyrene) is a cation-exchange resin used to treat high levels of potassium in the blood, also called hyperkalemia. Kayexalate works by helping your body get rid of extra potassium. Kayexalate is available in generic form.
