Infection. In both children and adults, infections are the most common cause of an elevated platelet count. 2 This elevation can be extreme, with platelet counts greater than 1 million cells per microliter.
What does it mean if your platelet count is high?
A high platelet count can occur when something causes the bone marrow to make too many platelets. When the reason is unknown, it is called primary or essential thrombocytosis. When excess platelets are due to an infection or other condition, it is called secondary thrombocytosis.
What should I do if my platelet count is high?
Your doctor might prescribe platelet-lowering drugs primarily in the form of hydroxyurea (Droxia, Hydrea) or interferon alfa (Intron A). Platelets can be removed from your blood by a procedure that’s similar to dialysis.
What cancers cause high platelets?
A very high platelet count was associated with colon (OR, 4.38; 95% CI, 4.22-4.54), lung (OR, 4.37; 95% CI, 4.22-4.53), ovarian (OR, 4.62; 95% CI, 4.19-5.09), and stomach (OR, 4.27; 95% CI, 3.91-4.66) cancers. Odds ratios attenuated with increasing time from CBC test to cancer diagnosis.
Should I worry about a slightly elevated platelet count?
However, an abnormally high platelet count means that clotting could happen spontaneously. Blood clots may occur anywhere in the body, but are most common in the hands, feet and brain. Other symptoms of high platelet count include headaches, dizziness, weakness and fainting.
What autoimmune disease causes high platelets?
Hughes syndrome, or antiphospholipid antibody syndrome (APS), is an autoimmune condition that causes thickening of the circulating blood. The immune system produces abnormal blood proteins called antiphospholipid antibodies, which cause blood platelets to clump together.
What infections cause high platelet count?
Essential thrombocythemia (ET) was the most common cause of primary thrombocytosis. Among secondary, non-infectious etiologies, tissue damage was the most common, followed by malignancy and iron-deficiency anemia. The most common infectious causes of thrombocytosis were soft-tissue, pulmonary and GI infections.
Can stress cause high platelets?
Stressful life events and anxiety usually cause an increase in platelet volume and activity through various mechanisms.
Can vitamin D deficiency cause high platelet count?
Increased platelet counts were found in people with low vitamin D levels.
What is the alarming level of platelets?
Having more than 450,000 platelets is a condition called thrombocytosis; having less than 150,000 is known as thrombocytopenia. You get your platelet number from a routine blood test called a complete blood count (CBC).
How can I lower my mean platelet naturally?
Decreasing MPV
Address Underlying Conditions. A high MPV is often due to an underlying medical condition. Lose Weight. Diabetes and obesity are associated with higher MPV [21, 19]. Check Vitamin D Levels. Check your vitamin D levels. Stop Smoking.
How do I bring my platelets down?
A medical procedure called plateletpheresis is used only in emergencies, such as after a stroke or other dangerous blood clotting. It involves passing your blood through a device that removes platelets and then returns the blood to your body. This temporarily lowers your platelet count.
How can I lower my platelet count?
Diets such as Mediterranean diet, high in omega-3 polyunsaturated fatty acids (PUFA), and vegetarian diets have inverse relationships with CVD. Dark chocolate, foods with low glycemic index, garlic, ginger, omega-3 PUFA, onion, purple grape juice, tomato, and wine all reduce platelet aggregation.
