Derek Shepherd dies in Season 11, Episode 21 of “Grey’s Anatomy.”

Does Derek Shepherd die in Season 11 episode 21?

Ultimately, Shonda Rhimes announced that Dempsey would no longer be on the show. After almost a decade in the medical drama, Derek died in Season 11, Episode 21, “How to Save a Life.”

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Derek Shepherd (Patrick Dempsey) — aka McDreamy, aka Meredith’s one true love — died in a car accident in season 11. “The decision to have the character die the way he did was not a difficult one in the sense of, what were the options,” show creator Shonda Rhimes said in 2015.

Why did Derek leave GREY’s anatomy?

Patrick Dempsey’s stunning exit from “Grey’s Anatomy” in 2015 came after his mood on the set was less than dreamy, according to a new book about the show.

Kate Walsh joined the medical drama as Derek’s wife, bringing up the third angle of the love triangle that Meredith and Derek found themselves in. She then came to Seattle to put things right with Derek. However, their marriage was soon cut short when Derek cheated on her with Meredith.