Common side effects may include: headache; or. cold symptoms such as stuffy nose, sinus pain, sore throat.
Alogliptin side effects
severe or ongoing pain in your joints;heart problems–shortness of breath (even while lying down), rapid weight gain, swelling (especially in your feet, legs, or midsection);
What is the best time of day to take alogliptin?
You can generally take alogliptin at a time of day to suit you, but it is best to take your doses at the same time of day each day. Swallow the tablet with a drink of water – you can take it either with or without food.
Is alogliptin any good?
Results of the large, well designed EXAMINE trial revealed that alogliptin was not associated with an increased risk of major cardiovascular events in patients with type 2 diabetes and recent acute coronary syndrome. In conclusion, alogliptin is a useful option for the treatment of patients with type 2 diabetes.
What are the benefits of alogliptin?
Alogliptin helps to control blood sugar levels by increasing substances in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.
Is alogliptin hard on kidneys?
Our study suggests that alogliptin can be safely administered in patients with CKD. However, although we expected alogliptin to demonstrate renal protective effects, were unable to detect statistically significant differences. One reason for this finding is that there are few registered cases.
Who should not take alogliptin?
Alogliptin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated).
What is the side effects of alogliptin 25 mg?
Rare
Blistering, peeling, or loosening of the skin.dark-colored urine.difficulty with swallowing.feeling of discomfort.general feeling of tiredness or weakness.headache.hives, itching, or rash.inflammation of the joints.
What is the difference between alogliptin and metformin?
Metformin, a biguanide, works by lowering the amount of sugar your liver releases into your blood and helps your body respond better to insulin. Alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, works by increasing the amount of insulin your body makes.
How much does alogliptin lower blood sugar?
It is reported that a 0.72% reduction in HbA1c levels with alogliptin add-on therapy for metformin for 2 years was observed in patients with type 2 diabetes [8].
Does alogliptin cause heart failure?
[ 4-5-2016 ] A U.S. Food and Drug Administration (FDA) safety review has found that type 2 diabetes medicines containing saxagliptin and alogliptin may increase the risk of heart failure, particularly in patients who already have heart or kidney disease.
What is the difference between alogliptin and Januvia?
Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don’t want to use an injectable medicine. Lowers your blood sugar. Nesina (alogliptin) is a good add-on treatment for diabetes if your blood sugars are still not controlled, but it doesn’t work as well as insulin.
Can I take alogliptin and metformin together?
Alogliptin and metformin combination may be used alone or together with other medicines and with a proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes. Alogliptin helps to control blood sugar levels by increasing substances in the body that make the pancreas release more insulin.
Is alogliptin good for diabetes?
Proper control of diabetes may also lessen your risk of a heart attack or stroke. Alogliptin works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.
Does alogliptin cause joint pain?
The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines sitagliptin, saxagliptin, linagliptin, and alogliptin may cause joint pain that can be severe and disabling.
How quickly does alogliptin work?
How long does it take for Nesina (alogliptin) to work? While you may see some effect after 2 weeks, it could take 18 to 20 weeks before you see the full effects of this medication on lowering your blood sugar and improving your A1c level.
Does alogliptin cause pancreatitis?
In rather short-term clinical trials with well-selected diabetic patients, no increased risk of acute pancreatitis has been observed with any of the five commercialized DPP-4 inhibitors: sitagliptin, vildagliptin, saxagliptin, alogliptin, and linagliptin.
What happens if you take too much alogliptin?
Symptoms of a serious allergic reaction to alogliptin may include: swelling of your face, lips, throat, and other areas on your skin. difficulty with swallowing or breathing. raised, red areas on your skin (hives)
Does alogliptin increase blood pressure?
In a nutshell
The authors concluded that alogliptin was associated with improved blood sugar control, BP and arterial stiffness in these patients.
