A large proportion of patients treated with paroxetine, mirtazapine, and other antidepressants, such as venlafaxine (EFFEXOR®, EFFEXOR XR®), gain a significant amount of weight.

Is Effexor making me gain weight?

Effexor and Serzone generally do not cause weight gain, while Wellbutrin can cause weight loss. Sometimes switching within the same class of drugs can make a huge difference.

Can you lose weight on Effexor?

Weight gain or weight loss can occur in people taking Effexor XR. But these were not common side effects reported in studies of Effexor XR.