Vitamin B1 (Thiamine)

Vitamin B1 deficiency can cause heavy and tired legs after running, muscle cramps, fatigue, and odd sensations in your legs and feet.

Can too many vitamins cause leg pain?

How too much can hurt: Vitamin D blood levels exceeding 100 ng/mL can be dangerous. The extra vitamin D triggers extra calcium absorption. This can cause muscle pain, mood disorders, abdominal pain and kidney stones.

Can vitamin D cause leg aches?

A vitamin D deficiency can affect both physical and mental health, but many people have low levels of vitamin D without realizing. The physical symptoms of a deficiency may include muscle pain in the joints, including rheumatoid arthritis (RA) pain, which often occurs in the knees, legs, and hips.