Hemophilia is caused by a mutation or change, in one of the genes, that provides instructions for making the clotting factor How does hemophilia affect the liver? how do doctors and researchers decide whether a disease is a good candidate for gene therapy?.

How does hemophilia affect the circulatory system?

Hemophilia is a disease that causes problems with blood clotting. It makes people’s blood clot (coagulate) much more slowly than usual. This means that wounds take longer to heal. When blood doesn’t clot properly, it can lead to bleeding inside the body too – for instance, following a fall or a crush injury.

Is hemophilia A hemostasis disorder?

Hemophilia is usually an inherited bleeding disorder in which the blood does not clot properly. This can lead to spontaneous bleeding as well as bleeding following injuries or surgery. Blood contains many proteins called clotting factors that can help to stop bleeding.