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Simply so, how can the meaning of IR and SER be determined in the Preterit?

They are two different verbs that mean two different things although they share the same conjugation in the preterite. Ser means “to be” (essence) and ir means “to go”.

Also Know, how do you use ser and ir? The verb ir for example is often followed by the preposition a while ser is usually not. Jubilado nailed it. These verbs separate themselves better in the past tense in the imperfect form. Also, usually to communicate the past tense of "ser" for something "you were" you would use the imperfect.

In this manner, what does IR mean in preterite?

IR - to go. Yo fui. I went. Tú fuiste. You (sing/inf) went.

What do ser and ir mean?

They are two different verbs that mean two different things although they share the same conjugation in the preterite. Ser means “to be” (essence) and ir means “to go”.