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Herein, how much are levigating agents?
Cards
| Term Semisolid Definition | Definition Attribute of a material characterized by a reduced ability to flow or conform to its container at room temperature. |
|---|---|
| Term How much levigating agent to use? | Definition 4-6% w/w ; use specific gravity |
Additionally, what is Levigation in pharmacy? Levigation. Levigation is the process of grinding an insoluble substance to a fine powder, while wet. The material is introduced into the mill together with water, in which the powdered substance remains suspended, and flows from the mill as a turbid liquid or thin paste, according to the amount of water employed.
Also to know, how do I choose a levigating agent?
If the drug will reside in the internal phase (water phase), then the levigating agent should be water soluble or miscible. Water, glycerin, alcohol, or propylene glycol would be suitable levigating agents. If the drug will reside in the external phase, then mineral oil should be used.
What is Levigation in compounding?
Levigation reduces the particle size by triturating it in a mortar or spatulating it on an ointment slab or pad with a small amount of a liquid in which the solid is not soluble. This method is also used to reduce the particle size of insoluble materials when compounding ointments and suspensions.
What is a hydrophilic base?
How do I make ointment?
- Melt the stearyl alcohol and white petrolatum on a hot plate.
- Heat this mixture to 70°C.
- Dissolve remaining ingredients in water and heat the solution to 70° C.
- Add the oleaginous phase slowly to the aqueous phase, stirring constantly.
- Remove from heat and stir the mixture until it congeals.
