Metronidazole has activity against protozoans like Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis, for which the drug was first approved as an effective treatment. Anaerobic bacteria which are typically sensitive are primarily Gram-negative anaerobes belonging to the Bacteroides and Fusobacterium spp.

Is there an antidote for Flagyl?

Treatment: There is no specific antidote for Flagyl overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

How do you neutralize metronidazole?

Neutralization for Intravenous Infusion: Neutralize the intravenous solution containing FLAGYL I.V. with approximately 5 mEq of sodium bicarbonate injection for each 500 mg of FLAGYL I.V. used. Mix thoroughly. The pH of the neutralized intravenous solution will be approximately 6.0 to 7.0.