What causes peripheral vascular disease? The most common cause of PVD is atherosclerosis, the buildup of plaque inside the artery wall. Plaque reduces the amount of blood flow to the limbs. It also decreases the oxygen and nutrients available to the tissue.

What is the most common cause of PVD?

Peripheral vascular disease causes The primary cause of PVD is atherosclerosis, a slowly developing condition in which fatty deposits cling to an artery wall. To heal the damage, an artery wall releases chemicals that encapsulate and stabilize the plaque.

Can PVD be reversed?

If peripheral vascular disease goes untreated, there is a chance that it may progress into critical limb ischemia, a severe stage of PVD that can result in the loss of an affected limb. But if caught in its early stages, peripheral vascular disease is a treatable and reversible disease.