R421A is a HFC blend replacement with zero ODP and is compatible with both synthetic and mineral oils. R421A is a two-component blend packaged with a proprietary lubricant which we recommend be transferred from the cylinder in the liquid phase. … Charge the equipment with R421A as a liquid.

What refrigerant does R421A replace?

R-421A is a drop-in replacement for R22 systems. With this refrigerant there is no need to change the oil. Simply recover the R22 and recharge with R421A.

Can R417A be mixed with R22?

So, the R22 can be replaced by R417A in both new and existing plants. This is because, differently from R407C and R507 that require use of polyester oil, the R417A does not require a change of lubricant type since it is compatible with mineral, alkyl benzene and ester oils.