In one study on both men and women with hypertension (high blood pressure) who were lysine-deficient, taking lysine supplements brought down their blood pressure.

Is L-Lysine good for high blood pressure?

Lysine could directly help reduce BP of hypertensive individuals whose lysine intakes are low. Lysine could also have control over the abnormal responses to stressors/anxiety which is known to influence heart beats and therefore on hypertension.

Does L-Lysine raise heart rate?

Of note, L-lysine increased force of contraction in a concentration- and time-dependent manner in isolated electrically paced left atrium of mouse and in human right atrium. It further increased heart rate and left ventricular pressure in the isolated perfused mouse heart.