The best control is achieved by using a weed control product that contains glyphosate, such as Round-Up. Now would be the best time to spray to control Centipede. Unfortunately, glyphosate is a non selective weed control and will kill both the desired and undesired grasses.

Will vinegar kill centipede grass?

Spraying vinegar over your entire lawn is not the best way to control weeds. It might kill the weeds, but it’s just as likely to kill the grass. … A drop or two shouldn’t harm the grass, but more than that can burn the blades along with the weeds.

Will Roundup kill dormant centipede grass?

If you apply glyphosate (Roundup, etc) to your “dormant” lawn now you will kill your centipedegrass. A better option is to spot spray with a broadleaf weedkiller labeled for use on centipedegrass, paying particular attention to the mixing rate. Due to the cold weather, you’ll begin to see weed control in two weeks.