The hypodermis is the bottom layer of your skin, located below the epidermis (top layer) and dermis (middle layer) in your skin.

Where is the hypodermis layer of the skin located?

The hypodermis (also called the subcutaneous layer or superficial fascia) is a layer directly below the dermis and serves to connect the skin to the underlying fascia (fibrous tissue) of the bones and muscles.

Where is the hypodermis in relation to the epidermis?

The hypodermis is deep to the dermis and is also called subcutaneous fascia. It is the deepest layer of skin and contains adipose lobules along with some skin appendages like the hair follicles, sensory neurons, and blood vessels.