The duodenum is the first part of the small intestine. The main role of the duodenum is to complete the first phase of digestion. In this section of the intestine, food from the stomach is mixed with enzymes from the pancreas and bile from the gallbladder. The enzymes and bile help break down food.

What is the duodenum and how does it work?

The duodenum, the first and shortest section of the small intestine, is a key organ in the digestive system. The small intestine’s most important function is to digest nutrients and pass them into the blood vessels—located in the intestinal wall—for absorption of the nutrients into the bloodstream.

Can you survive without a duodenum?

If the pyloric valve located between the stomach and first part of the small intestine (duodenum) is removed, the stomach is unable to retain food long enough for partial digestion to occur. Food then travels too rapidly into the small intestine producing a condition known as the post-gastrectomy syndrome.