Leukotrienes are inflammatory chemicals the body releases after coming in contact with an allergen or allergy trigger. Leukotrienes cause tightening of airway muscles and the production of excess mucus and fluid.

What is the use of leukotrienes?

Leukotriene modifiers, also called leukotriene receptor antagonists, are a group of medications. They can help prevent breathing problems associated with allergies, asthma and chronic obstructive pulmonary disease.

What do leukotrienes do in the brain?

Leukotrienes mediate edema and blood-brain barrier permeability after TBI. Leukotriene production contributes to lasting deficits in memory and learning. Blocking leukotriene synthesis attenuates brain injury and cognitive impairments. FLAP inhibitors are promising therapeutic candidates for traumatic brain injury.