Too little CO2 in the blood may indicate: Addison’s disease, another disorder of the adrenal glands. In Addison’s disease, the glands don’t produce enough of certain types of hormones, including cortisol. The condition can cause a variety of symptoms, including weakness, dizziness, weight loss, and dehydration.

What can cause CO2 levels to be low?

• Addison’s disease.
• diarrhea.
• poisoning with ethylene glycol, such as from antifreeze poisoning.
• ketoacidosis, wherein the body produces too many blood acids.
• kidney disease.
• salicylate toxicity, such as from an aspirin overdose.
• lactic acidosis, or a buildup of lactate in the body.

What does it mean when someone's CO2 is low?

Lower levels of carbon dioxide may mean you have: Metabolic acidosis, or your blood is too acidic. Addison disease, an adrenal gland problem. Ketoacidosis.