Sleep and eat more or less than usual (for most people it is less) Low energy, trouble concentrating, or thoughts of death (suicidal thinking) Psychomotor agitation (‘nervous energy’) Psychomotor retardation (feeling like you are moving and thinking in slow motion)

How effective is Parnate for severe depression?

User Reviews for Parnate to treat Depression. Parnate has an average rating of 8.7 out of 10 from a total of 79 ratings for the treatment of Depression. 89% of reviewers reported a positive effect, while 8% reported a negative effect.

How long do Parnate side effects last?

Maximum plasma concentrations can occur within one to two hours of taking the Parnate. The pharmacodynamic effects of Parnate can last several days because of the irreversible effects that it has on the breakdown of certain neurotransmitters.