Lipid rafts—ordered assemblies of sphingolipid, cholesterol, and certain membrane proteins—are thought to be key components for the dynamic compartmentalization.

How lipids are arranged in the membrane?

As a result, the lipid components of membranes are arranged in what may be called a continuous bimolecular leaflet, or bilayer. … The polar portions of the constituent molecules lie in the two bilayer faces, while the nonpolar portions constitute the interior of the bilayer.

What is lipid order?

High lipid order protects membranes from perforin binding. To assess perforin binding and pore formation on membranes of defined lipid composition, we used atomic force microscopy (AFM) on supported lipid bilayers6,17,18,19,20.