DCT cells are largely water impermeable, and reabsorb sodium and chloride across the apical membrane via electroneurtral pathways. Prominent among this is the thiazide-sensitive sodium chloride cotransporter, target of widely used diuretic drugs.

What does the DCT absorb?

Early Distal Convoluted Tubule The role of the early DCT is the absorption of ions, including sodium, chloride and calcium. It is impermeable to water. The macula densa are situated in the first segment of the DCT – these are the sensing epithelium involved in tubuloglomerular feedback.

Which is finally reabsorbed in DCT?

The distal convoluted tubules (DCT) is the last passage of magnesium reabsorption in the nephrons, as no further reabsorption occurs beyond this segment. Of the total magnesium reabsorption 10% takes place in the DCT (Brunette, Vigneault, & Carriere, 1974).