Prontosil was introduced into medicine in the 1930s. Prontosil resulted from research, directed by German chemist and pathologist Gerhard Domagk

When did sulfonamides become available?

Introduced in 1935 by Gerhard Domagk (1895–1964), sulfa drugs, or sulfonamides, all of which are related to the compound sulfanilamide, provided the first successful therapies for many bacterial diseases.

When was Prontosil released?

17.2. In the early twentieth century, Gerhart Domagk started to examine the antibacterial activity of synthetic sulfonamides, which led him to discover Prontosil, a red azo dye, in 1932. It could destroy streptococci (Fig. 17.3).