Chelex 100 is a chelating material from Bio-Rad used to purify other compounds via ion exchange. … Chelex resin is often used for DNA extraction in preparation for polymerase chain reaction by binding to cations including Mg2+, which is an essential cofactor for DNases.

What is the Chelex DNA extraction method?

Principle: Chelex resin works by preventing DNA degradation from degradative enzymes (DNases) and from potential contaminants that might inhibit downstream analyses. In general, the Chelex resin will trap such contaminants, leaving DNA in solution.

Is Chelex safe?

Not a dangerous substance or mixture according to the Globally Harmonised System (GHS). Inhalation May be harmful if inhaled. May cause respiratory tract irritation. … May cause skin irritation.