Mononucleosis rarely leads to a serious condition called chronic EBV infection. In chronic EBV infection, you have long-lasting symptoms and a viral infection that lasts longer than usual after your original mononucleosis diagnosis.

What are the long term effects of mononucleosis?

If a teenager or adult is infected, they may experience symptoms like fatigue, swollen lymph nodes, and fever. In very rare cases, EBV can cause a chronic infection, which can be fatal if left untreated. EBV has also been linked with a variety of conditions, including cancers and autoimmune disorders.

Do you ever fully recover from mono?

It takes two to three months to completely recover from mononucleosis. Most of the people infected with mononucleosis may start to feel better within two to four weeks, but fatigue may last longer. It generally takes two to three months to completely recover from mononucleosis.