Some studies have shown that sucralose can change your gut microbiome by lowering the number of good bacteria by half. Research done on animals shows that sucralose can also increase inflammation in the body. Over time, inflammation can lead to problems like obesity and diabetes.

Is sucralose actually bad?

Yet scientists haven’t found any direct negative health effects in people who consume sucralose long-term. That’s true both for healthy people and those with diabetes. “While sucralose may cause problems at higher doses, most people consume nowhere near that amount,” says Patton.

Which is the safest artificial sweetener?

The best and safest artificial sweeteners are erythritol, xylitol, stevia leaf extracts, neotame, and monk fruit extract—with some caveats: Erythritol: Large amounts (more than about 40 or 50 grams or 10 or 12 teaspoons) of this sugar alcohol sometimes cause nausea, but smaller amounts are fine.