During depolarization, the membrane potential rapidly shifts from negative to positive. … As the sodium ions rush back into the cell, they add positive charge to the cell interior, and change the membrane potential from negative to positive.

What happens during depolarization in the heart?

What is meant by depolarization of the heart? Depolarization of the heart is the orderly passage of electrical current sequentially through the heart muscle, changing it, cell by cell, from the resting polarized state to the depolarized state until the entire heart is depolarized.

What Depolarizes the interventricular septum?

During ventricular activation, impulses are first conducted down the left and right bundle branches on either side the septum. This causes the septum to depolarize from left-to-right as depicted by vector 1 (Panel A).