Ductal cells of the pancreas form the epithelial lining of the branched tubes that deliver enzymes produced by pancreatic acinar cells

What is released by the duct cells?

Ductal cells refer to cells lining the pancreatic duct and are responsible for production of bicarbonate-rich secretion. Ductal cells are stimulated by the hormone secretin and are responsible for maintenance of the duodenal pH and prevention of duodenal injury from acidic chyme.

Where is HCO3 secreted?

HCO3- -rich fluid in the pancreatic juice (2-3 L/day) is secreted by epithelial cells lining the pancreatic duct tree, while digestive enzymes are secreted by acinar cells with a small amount of Cl- -rich fluid.