Alcohol (ethyl alcohol or ethanol)Alprazolam (Xanax)Chloral hydrate (Somnote)Chlordiazepoxide (Librium)Clorazepate (Tranxene)Clonazepam (Klonopin)Diazepam (Valium)Estazolam (Prosom)

What is the most sedating drug?

Sedatives can be used to produce an overly-calming effect (alcohol being the most common sedating drug). In the event of an overdose or if combined with another sedative, many of these drugs can cause deep unconsciousness and even death.

Are tranquilizers sedatives?

Sedatives are a category of drugs that slow brain activity. Also known as tranquilizers or depressants, sedatives have a calming effect and can also induce sleep.