The effects of vitamin K toxicity can include jaundice in newborns, hemolytic anemia, and hyperbilirubinemia. Toxicity also blocks the effects of oral anticoagulants.

Does vitamin K affect the liver?

There is no evidence that vitamin K supplementation, in physiologic or even higher doses, causes serum enzyme elevations, liver injury or jaundice.

Does vitamin K break down bilirubin?

The concentration of bilirubin in the serum in a group of 119 premature and full-term infants was studied after the administration of water-soluble vitamin K and vitamin K1. It appeared that large doses of water-soluble vitamin K produced a higher concentration of bilirubin than was found in the control infants.