The nuclear envelope keeps the contents of the nucleus, called the nucleoplasm, separate from the cytoplasm of the cell. The all-important genetic material, mainly the DNA is kept separate and relatively safe from the chemical reactions taking place in the cytoplasm.

What is the nuclear envelope in mitosis?

The nuclear envelope, including nuclear pore complexes, breaks down at the beginning of mitosis to accommodate the capture of massively condensed chromosomes by the spindle apparatus. At the end of mitosis, a nuclear envelope is newly formed around each set of segregating and de-condensing chromatin.

What is the nuclear envelope made up of?

The nuclear envelope is a double membrane composed of an outer and an inner phospholipid bilayer. The thin space between the two layers connects with the lumen of the rough endoplasmic reticulum (RER), and the outer layer is an extension of the outer…