pD2. pD2 is the negative logarithm of an EC50 or IC50 value.

What is a pA2 value?

In the field of biochemistry, a pA2 value determines the important relationship between two drugs “competing” for effect on the same receptor. … The pA2 value indicates the concentration of antagonist when double the agonist is required to have the same effect on the receptor as when no antagonist is present.

What does a Schild plot show?

In pharmacology, Schild regression analysis, named for Heinz Otto Schild, is a tool for studying the effects of agonists and antagonists on the response caused by the receptor or on ligand-receptor binding. and can be used to quantify the strength of the antagonist.